“Chemical zymogens for the protein cysteinome“ https://doi.org/10.1038/s41467-022-32609-1 We present three classes of chemical zymogens established around the protein cysteinome. In each case, the cysteine thiol…
We are currently looking for talented colleagues to join our team at the front-line of research. If you are an experienced researcher with interests at…
“Dimerization of the Peptide CXCR4-Antagonist on Macromolecular and Supramolecular Protraction Arms Affords Increased Potency and Enhanced Plasma Stability“ https://doi.org/10.1021/acs.bioconjchem.2c00034 Peptides are prime drug candidates due…
Check out two of our most recent results in artificial signaling systems Transmembrane signalling by a bionic receptor: biological input and output, chemical mechanism of…
Our work “Ceria Nanozyme and Phosphate Prodrugs: Drug Synthesis through Enzyme Mimicry” has been published in ACS Applied Materials & Interfaces. Nanozymes can mimic the…
Our work “Synthetic Artificial Apoptosis-Inducing Receptor for On-Demand Deactivation of Engineered Cells” has been published in Advanced Science The design of a fully synthetic, chemical…
Our review “Synthetic chemical ligands and cognate antibodies for biorthogonal drug targeting and cell engineering” has been published in Advanced Drug Delivery Reviews A vast…
Our work “Nanozymes and Glucuronides: Glucuronidase, Esterase, and/or Transferase Activity” giving mechanistic insights on the degradation of glucuronides by nanozymes has been published in Small.…
Come read about the results of our ERC project – in six languages !