Artificial Receptor in Synthetic Cells Performs Transmembrane Activation of Proteolysis Søgaard, A. B., Løvschall, K. B., Montasell, M. C., Cramer C. B., Marcet, P. M., Pedersen, A. B., Jakobsen, J. H.,…
On Friday April 19th 2024 Professor Alexander N. Zelikin successfully defended his doctoral thesis: Prodrugs: Molecular, macromolecular, and supramolecular opportunities in drug delivery. This was…
Artificial Internalizing Receptor Affords Fast, Potent, Specific Drug Delivery to the Chemically Engineered Cells Søgaard, A. B., Skovbo, F., Tvilum, A., Hansson, R. F., Zelikin, A. N., Artificial Internalizing Receptor…
Zymogens and Transmembrane Activation of Transcription in Synthetic Cells Andersen, D. G., Pedersen, A. B., Jørgensen, M. H., Montasell, M. C., Søgaard, A. B., Chen, G., Schroeder, A., Andersen, G. R., Zelikin, A.…
The scariest time of the year was celebrated in style with a costume party on the night of Halloween 🎃
Mechanisms of Degradation for Polydisulfides: Main Chain Scission, Self-Immolation, Or Chain Transfer Depolymerization Kristensen, M. M.; Løvschall, K. B.; Zelikin, A. N., Mechanisms of Degradation…
“Antibody-Drug Conjugates to Treat Bacterial Biofilms viaTargeting and Extracellular Drug Release” https://doi.org/10.1002/advs.202301340 Abstract The treatment of implant-associated bacterial infections and biofilms is an urgent medical…
“Chemical zymogens: specificity and steroidal control ofreactivation” https://doi.org/10.1002/cbic.202300304 Abstract: Activation and masking of enzymatic activity on demand is of the highest importance in nature. It…
Signal transduction across biological membranes is among the most important evolutionary achievements. Herein, for the design of artificial cells, weengineer fully synthetic receptors with the…
On Friday February 24th 2023, Josefine Hammer Jakobsen successfully defended her PhD thesis with the title “Diversity of the Prodrug Design – In Treatment of…