Publications

Full list of publications

Aarhus University

2019

	"Non-covalent hitchhiking on endogenous carriers as a protraction mechanism for antiviral macromolecular prodrugs" Frich, Camilla Kaas; Krüger, Franziska; Walther, Raoul; Domar, Cecilie; Andersen, Anna H. F.; Tvilum, Anne; Dagnæs-Hansen, Frederik; Denton, Paul W.; Tolstrup, Martin; Paludan, Søren R.; Münch, Jan; Zelikin, Alexander N. Journal of Controlled Release 2019, 294(), 298-310
	"Innate glycosidic activity in metallic implants for localized synthesis of antibacterial drugs" ter Meer, Marja; Dillion, Ross; Nielsen, Signe Maria; Walther, Raoul; Meyer, Rikke L.; Daamen, Willeke F.; van den Heuvel, Lambertus P.; van der Vliet, J. Adam; Lomme, Roger M. L. M.; Hoogeveen, Yvonne L.; Schultze Kool, Leo J.; Schaffer, Jeremy E.; Zelikin, Alexander N. Chemical Communications 2019, 56(4), 443-446
	"Identification and Directed Development of Non-Organic Catalysts with Apparent Pan-Enzymatic Mimicry into Nanozymes for Efficient Prodrug Conversion" Walther, Raoul; Winther, Anna K.; Fruergaard, Anne Sofie; van den Akker, Wouter; Sørensen, Lise; Nielsen, Signe Maria; Jarlstad Olesen, Morten T.; Dai, Yitao; Jeppesen, Henrik S.; Lamagni, Paolo; Savateev, Aleksandr; Pedersen, Søren Lykke; Frich, Camilla Kaas; Vigier-Carrière, Cécile; Lock, Nina; Singh, Mandeep; Bansal, Vipul; Meyer, Rikke L.; Zelikin, Alexander N. Angewandte Chemie International Edition 2019, 58(1), 278-282

2018

	"Long-Acting, Potent Delivery of Combination Antiretroviral Therapy" Andersen, Anna H. F.; Riber, Camilla F.; Zuwala, Kaja; Tolstrup, Martin; Dagnæs-Hansen, Frederik; Denton, Paul W.; Zelikin, Alexander N. ACS Macro Letters 2018, 7(5), 587-591
	"Bi-Enzymatic Embolization Beads for Two-Armed Enzyme-Prodrug Therapy" Olesen, Morten T. Jarlstad; Winther, Anna K.; Fejerskov, Betina; Dagnaes-Hansen, Frederik; Simonsen, Ulf; Zelikin, Alexander N. ADVANCED THERAPEUTICS 2018, 0(0), 1800023
	"The molecular tweezer CLR01 inhibits Ebola and Zika virus infection" Röcker, Annika E.; Müller, Janis A.; Dietzel, Erik; Harms, Mirja; Krüger, Franziska; Heid, Christian; Sowislok, Andrea; Riber, Camilla Frich; Kupke, Alexandra; Lippold, Sina; von Einem, Jens; Beer, Judith; Knöll, Bernd; Becker, Stephan; Schmidt-Chanasit, Jonas; Otto, Markus; Vapalahti, Olli; Zelikin, Alexander N.; Bitan, Gal; Schrader, Thomas; Münch, Jan Antiviral Research 2018, 152(), 26-35
	"Enzyme Prodrug Therapy Achieves Site-Specific, Personalized Physiological Responses to the Locally Produced Nitric Oxide" Winther, Anna K.; Fejerskov, Betina; ter Meer, Marja; Jensen, Najah B. S.; Dillion, Ross; Schaffer, Jeremy E.; Chandrawati, Rona; Stevens, Molly M.; Schultze Kool, Leo J.; Simonsen, Ulf; Zelikin, Alexander N. ACS Applied Materials & Interfaces 2018, 10(13), 10741-10751
	"Macromolecular prodrugs of ribavirin: Polymer backbone defines blood safety, drug release, and efficacy of anti-inflammatory effects" Zuwala, Kaja; Riber, Camilla F.; Løvschall, Kaja Borup; Andersen, Anna H. F.; Sørensen, Lise; Gajda, Paulina; Tolstrup, Martin; Zelikin, Alexander N. Journal of Controlled Release 2018, 275(), 53-66

2017

	"Macromolecular Antiviral Agents against Zika, Ebola, SARS, and Other Pathogenic Viruses" Schandock, Franziska; Riber, Camilla Frich; Röcker, Annika; Müller, Janis A.; Harms, Mirja; Gajda, Paulina; Zuwala, Kaja; Andersen, Anna H. F.; Løvschall, Kaja Borup; Tolstrup, Martin; Kreppel, Florian; Münch, Jan; Zelikin, Alexander N. Advanced Healthcare Materials 2017, 6(23), 1700748
	"Synthetic Polymer with a Structure-Driven Hepatic Deposition and Curative Pharmacological Activity in Hepatic Cells" Riber, Camilla Frich; Andersen, Anna Halling Folkmar; Rolskov, Lærke Anegaard; Zuwala, Kaja; Gajda, Paulina; Løvschall, Kaja Borup; Dagnæs-Hansen, Frederik; Banda, Dominic H.; Pietschmann, Thomas; Tolstrup, Martin; Zelikin, Alexander N. ACS Macro Letters 2017, (), 935-940
	"Enzyme Prodrug Therapy Engineered into Electrospun Fibers with Embedded Liposomes for Controlled, Localized Synthesis of Therapeutics" Chandrawati, Rona; Olesen, Morten T. J.; Marini, Thatiane C. C.; Bisra, Gurpal; Guex, Anne Géraldine; de Oliveira, Marcelo G.; Zelikin, Alexander N.; Stevens, Molly M. Advanced Healthcare Materials , (), 1700385-n/a
	"Prodrugs in medicinal chemistry and enzyme prodrug therapies" Walther, Raoul; Rautio, Jarkko; Zelikin, Alexander N. Advanced Drug Delivery Reviews , 118(), 65-77
	"Recent advances in macromolecular prodrugs" Riber, Camilla Frich; Zelikin, Alexander N. Current Opinion in Colloid & Interface Science 2017, 31(), 1-9
	"Preparation, single-molecule manipulation and energy transfer investigation of a polyfluorene-graft-DNA polymer" Madsen, Mikael; Christensen, Rasmus S.; Krissanaprasit, Abhichart; Bakke, Mette R.; Riber, Camilla F.; Nielsen, Karina S.; Zelikin, Alexander; Gothelf, Kurt Vesterager Chemistry – A European Journal , (), n/a-n/a
	"Substrate Mediated Enzyme Prodrug Therapy" Fejerskov, Betina; Jarlstad Olesen, Morten T.; Zelikin, Alexander N. Advanced Drug Delivery Reviews 2017, (),
	"Localized and Controlled Delivery of Nitric Oxide to the Conventional Outflow Pathway via Enzyme Biocatalysis: Toward Therapy for Glaucoma" Chandrawati, Rona; Chang, Jason Y. H.; Reina-Torres, Ester; Jumeaux, Coline; Sherwood, Joseph M.; Stamer, W. Daniel; Zelikin, Alexander N.; Overby, Darryl R.; Stevens, Molly M. Advanced Materials 2017, 29(16), 1604932

2016

	"Macromolecular Prodrugs of Ribavirin: Structure–Function Correlation as Inhibitors of Influenza Infectivity" Riber, Camilla Frich; Hinton, Tracey M.; Gajda, Paulina; Zuwala, Kaja; Tolstrup, Martin; Stewart, Cameron; Zelikin, Alexander N. Molecular Pharmaceutics 2016, 14(1), 234-241
	"Materials and methods for delivery of biological drugs" Zelikin, Alexander N.; Ehrhardt, Carsten; Healy, Anne Marie Nat Chem 2016, 8(11), 997-1007
	"Albumin–Polymer–Drug Conjugates: Long Circulating, High Payload Drug Delivery Vehicles" Smith, Anton A. A.; Zuwala, Kaja; Pilgram, Oliver; Johansen, Karen Singers; Tolstrup, Martin; Dagnæs-Hansen, Frederik; Zelikin, Alexander N. ACS Macro Letters 2016, 5(10), 1089-1094
	"Triple Activity of Lamivudine Releasing Sulfonated Polymers against HIV-1" Danial, Maarten; Andersen, Anna H. F.; Zuwala, Kaja; Cosson, Steffen; Riber, Camilla Frich; Smith, Anton A. A.; Tolstrup, Martin; Moad, Graeme; Zelikin, Alexander N.; Postma, Almar Molecular Pharmaceutics 2016, 13(7), 2397-2410
	"Polyanionic Macromolecular Prodrugs of Ribavirin: Antiviral Agents with a Broad Spectrum of Activity" Hinton, Tracey M.; Zuwala, Kaja; Deffrasnes, Celine; Todd, Shawn; Shi, Shuning; Marsh, Glenn A.; Dearnley, Megan; Wohl, Benjamin M.; Tolstrup, Martin; Zelikin, Alexander N. Advanced Healthcare Materials 2016, 5(5), 534-540
	"HIV anti-latency treatment mediated by macromolecular prodrugs of histone deacetylase inhibitor, panobinostat" Zuwala, Kaja; Smith, Anton A. A.; Tolstrup, Martin; Zelikin, Alexander N. Chemical Science 2016, 7(3), 2353-2358
	"Tools of gene transfer applied to the intracellular delivery of non-nucleic acid polyanionic drugs" Kryger, Mille B. L.; Pedersen, Søren L.; Wohl, Benjamin M.; Zelikin, Alexander N. Chemical Communications 2016, 52(5), 889-891

2015

	"Phospholipid—polymer amphiphile hybrid assemblies and their interaction with macrophages" Panneerselvam, Karthiga; Lynge, Martin E.; Riber, Camilla Frich; Mena-Hernando, Sofia; Smith, Anton A. A.; Goldie, Kenneth N.; Zelikin, Alexander N.; Städler, Brigitte Biomicrofluidics 2015, 9(5), 052610
	"Routing of individual polymers in designed patterns" Knudsen, Jakob Bach; Liu, Lei; Bank Kodal, Anne Louise; Madsen, Mikael; Li, Qiang; Song, Jie; Woehrstein, Johannes B.; Wickham, Shelley F. J.; Strauss, Maximilian T.; Schueder, Florian; Vinther, Jesper; Krissanaprasit, Abhichart; Gudnason, Daniel; Smith, Anton Allen Abbotsford; Ogaki, Ryosuke; Zelikin, Alexander N.; Besenbacher, Flemming; Birkedal, Victoria; Yin, Peng; Shih, William M.; Jungmann, Ralf; Dong, Mingdong; Gothelf, Kurt V. Nat Nano 2015, 10(10), 892-898
	"Self-Immolative Linkers Literally Bridge Disulfide Chemistry and the Realm of Thiol-Free Drugs" Riber, Camilla Frich; Smith, Anton A. A.; Zelikin, Alexander N. Advanced Healthcare Materials 2015, 4(12), 1887-1890
	"Micro-structured, spontaneously eroding hydrogels accelerate endothelialization through presentation of conjugated growth factors" Jensen, Bettina E. B.; Edlund, Katrine; Zelikin, Alexander N. Biomaterials 2015, 49(0), 113-124
	"Macromolecular prodrugs of ribavirin: towards a treatment for co-infection with HIV and HCV" Smith, Anton A. A.; Zuwala, Kaja; Kryger, Mille B. L.; Wohl, Benjamin M.; Guerrero-Sanchez, Carlos; Tolstrup, Martin; Postma, Almar; Zelikin, Alexander N. Chemical Science 2015, 6(1), 264-269
	"Highly Active Macromolecular Prodrugs Inhibit Expression of the Hepatitis C Virus Genome in the Host Cells" Ruiz-Sanchis, Pau; Wohl, Benjamin M.; Smith, Anton A. A.; Zuwala, Kaja; Melchjorsen, Jesper; Tolstrup, Martin; Zelikin, Alexander N. Advanced Healthcare Materials 2015, 4(1), 65-68
	"Polymers Fight HIV: Potent (Pro)Drugs Identified Through Parallel Automated Synthesis" Zuwala, Kaja; Smith, Anton A. A.; Postma, Almar; Guerrero-Sanchez, Carlos; Ruiz-Sanchis, Pau; Melchjorsen, Jesper; Tolstrup, Martin; Zelikin, Alexander N. Advanced Healthcare Materials 2015, 4(1), 46-50

2014

	"Macromolecular (pro)drugs with concurrent direct activity against the hepatitis C virus and inflammation" Wohl, Benjamin M.; Smith, Anton A. A.; Jensen, Bettina E. B.; Zelikin, Alexander N. Journal of Controlled Release 2014, 196(0), 197-207
	"Disulfide reshuffling triggers the release of a thiol-free anti-HIV agent to make up fast-acting, potent macromolecular prodrugs" Kock, Anders; Zuwala, Kaja; Smith, Anton A. A.; Ruiz-Sanchis, Pau; Wohl, Benjamin M.; Tolstrup, Martin; Zelikin, Alexander N. Chemical Communications 2014, 50(93), 14498-14500
	"Macromolecular (pro)drugs in antiviral research" Smith, Anton A. A.; Kryger, Mille B. L.; Wohl, Benjamin M.; Ruiz-Sanchis, Pau; Zuwala, Kaja; Tolstrup, Martin; Zelikin, Alexander N. Polymer Chemistry 2014, 5(22), 6407-6425
	"Enzyme Prodrug Therapy Engineered into Biomaterials" Mendes, Ana C.; Zelikin, Alexander N. Advanced Functional Materials 2014, 24(33), 5202-5210
	"Cholesterol Modification of (Bio)Polymers Using UV-Vis Traceable Chemistry in Aqueous Solutions" Rasmussen, Kasper F.; Smith, Anton A. A.; Ruiz-Sanchis, Pau; Edlund, Katrine; Zelikin, Alexander N. Macromolecular Bioscience 2014, 14(1), 33-44
	"Biocatalytic polymer thin films: optimization of the multilayered architecture towards in situ synthesis of anti-proliferative drugs" Andreasen, Sidsel O.; Fejerskov, Betina; Zelikin, Alexander N. Nanoscale 2014, 6(8), 4131-4140
	"Macromolecular Prodrugs of Ribavirin: Concerted Efforts of the Carrier and the Drug" Smith, Anton A. A.; Wohl, Benjamin M.; Kryger, Mille B. L.; Hedemann, Natasha; Guerrero-Sanchez, Carlos; Postma, Almar; Zelikin, Alexander N. Advanced Healthcare Materials 2014, 3(9), 1404-1407
	"Biocatalytic Polymer Coatings: On-Demand Drug Synthesis and Localized Therapeutic Effect under Dynamic Cell Culture Conditions" Fejerskov, Betina; Jensen, Najah B. S.; Teo, Boon M.; Städler, Brigitte; Zelikin, Alexander N. Small 2014, 10(7), 1314-1324
	"Macromolecular Prodrugs for Controlled Delivery of Ribavirin" Kryger, Mille B. L.; Smith, Anton A. A.; Wohl, Benjamin M.; Zelikin, Alexander N. Macromolecular Bioscience 2014, 14(2), 173-185

2013

	"The narrow therapeutic window of ribavirin as an inhibitor of nitric oxide synthesis is broadened by macromolecular prodrugs" Wohl, Benjamin M.; Smith, Anton A. A.; Kryger, Mille B. L.; Zelikin, Alexander N. Biomacromolecules 2013, 14(11), 3916–3926
	"Lipogels: Surface-Adherent Composite Hydrogels Assembled from Poly(Vinyl Alcohol) and Liposomes" Jensen, Bettina; Hosta-Rigau, Leticia; Spycher, Philipp; Reimhult, Erik; Stadler, Brigitte; Zelikin, Alexander Nanoscale 2013, 5(), 6758-6766
	"Poly(vinyl alcohol) physical hydrogel nanoparticles, not polymer solutions, exert inhibition of nitric oxide synthesis in cultured macrophages" Andreasen, Sidsel; Chong, Siow-Feng; Wohl, Benjamin M.; Goldie, Kenneth N.; Zelikin, Alexander N. Biomacromolecules 2013, 14(5), 1687–1695
	"Liposomes as Drug Deposits in Multilayered Polymer Films" Lynge, Martin E.; Baekgaard Laursen, Marie; Hosta-Rigau, Leticia; Jensen, Bettina E. B.; Ogaki, Ryosuke; Smith, Anton A. A.; Zelikin, Alexander N.; Städler, Brigitte ACS Applied Materials & Interfaces 2013, 5(8), 2967–2975
	"Liposomal Templating, Association with Mammalian Cells, and Cytotoxicity of Poly(vinyl alcohol) Physical Hydrogel Nanoparticles" Andreasen, Sidsel Ø; Chong, Siow-Feng; Kryger, Mille B. L.; Jensen, Bettina E. B.; Postma, Almar; Alves, Marie-Helene; Städler, Brigitte; Goldie, Kenneth N.; Zelikin, Alexander N. Particle & Particle Systems Characterization 2013, 30(6), 514-522
	"Macromolecular Prodrugs of Ribavirin Combat Side Effects and Toxicity with No Loss of Activity of the Drug" Kryger, Mille; Wohl, Benjamin; Smith, Anton; Zelikin, Alexander Chemical Communications 2013, 49(), 2643-2645
	"Bioresorbable Surface Adhered Enzymatic Microreactors Based on Physical Hydrogels of Poly(vinyl alcohol)" Fejerskov, Betina; Smith, Anton A. A.; Jensen, Bettina E. B.; Hussmann, Thomas; Zelikin, Alexander N. Langmuir 2013, 29(1), 344–354
	"Microstructured, Functional PVA Hydrogels through Bioconjugation with Oligopeptides under Physiological Conditions" Chong, Siow-Feng; Smith, Anton A. A.; Zelikin, Alexander N. Small 2013, 9(6), 942–950

2012

	"Substrate Mediated Enzyme Prodrug Therapy" Fejerskov, Betina; Zelikin, Alexander N. PLoS ONE 2012, 7(11), e49619
	"Surface-Adhered Composite Poly(Vinyl Alcohol) Physical Hydrogels: Polymersome-Aided Delivery of Therapeutic Small Molecules" Hosta-Rigau, Leticia; Jensen, Bettina E. B.; Fjeldsø, Kit S.; Postma, Almar; Li, Guoxin; Goldie, Kenneth N.; Albericio, Fernando; Zelikin, Alexander N.; Städler, Brigitte Advanced Healthcare Materials 2012, (), n/a-n/a
	"Biodistribution of polymer hydrogel capsules for the delivery of therapeutics" Hinton, T. M.; Monaghan, P.; Green, D.; Kooijmans, S. A. A.; Shi, S.; Breheney, K.; Tizard, M.; Nicolazzo, J. A.; Zelikin, A. N.; Wark, K. Acta Biomaterialia 2012, 8(9), 3251-3260
	"Engineering Surface Adhered Poly(vinyl alcohol) Physical Hydrogels as Enzymatic Microreactors" Fejerskov, Betina; Jensen, Bettina E. B.; Jensen, Najah B. S.; Chong, Siow-Feng; Zelikin, Alexander N. ACS Applied Materials & Interfaces 2012, 4(9), 4981–4990
	"Surface adhered poly(vinyl alcohol) physical hydrogels as tools for rational design of intelligent biointerfaces" Jensen, B. E. B.; Alves, M. H.; Fejerskov, B.; Städler, B.; Zelikin, A. N. Soft Matter 2012, 8(17), 4625-4634
	"Intelligent Polymer Thin Films and Coatings for Drug Delivery" Zelikin, Alexander N.; Städler, Brigitte Book chapter in “Intelligent Surfaces in Biotechnology: Scientific and Engineering Concepts, Enabling Technologies, and Translation to Bio-Oriented Applications” 2012, (), 243-290
	"Macromolecular design of poly(vinyl alcohol) by RAFT polymerization" Smith, A. A. A.; Hussmann, T.; Elich, J.; Postma, A.; Alves, M. H.; Zelikin, A. N. Polymer Chemistry 2012, 3(1), 85-88

2011

	"Poly(vinyl alcohol) physical hydrogels: New vista on a long serving biomaterial" Alves, M. H.; Jensen, B. E. B.; Smith, A. A. A.; Zelikin, A. N. Macromolecular Bioscience 2011, 11(10), 1293-1313
	"Poly(vinyl alcohol) physical hydrogels: Noncryogenic stabilization allows nano- and microscale materials design" Jensen, B. E. B.; Smith, A. A. A.; Fejerskov, B.; Postma, A.; Senn, P.; Reimhult, E.; Pla-Roca, M.; Isa, L.; Sutherland, D. S.; Städler, B.; Zelikin, A. N. Langmuir 2011, 27(16), 10216-10223
	"Exploiting fluorescent polymers to probe the self-assembly of virus-like particles" Cadena-Nava, R. D.; Hu, Y.; Garmann, R. F.; Ng, B.; Zelikin, A. N.; Knobler, C. M.; Gelbart, W. M. Journal of Physical Chemistry B 2011, 115(10), 2386-2391
	"A critical look at multilayered polymer capsules in biomedicine: Drug carriers, artificial organelles, and cell mimics" Städler, B.; Price, A. D.; Zelikin, A. N. Advanced Functional Materials 2011, 21(1), 14-28

2010

	"Poly(methacrylic acid) polymer hydrogel capsules: Drug carriers, sub-compartmentalized microreactors, artificial organelles" Zelikin, A. N.; Städler, B.; Price, A. D. Small 2010, 6(20), 2201-2207
	"Drug releasing polymer thin films: New era of surface-mediated drug delivery" Zelikin, A. N. ACS Nano 2010, 4(5), 2494-2509

 The Univeristy of Melbourne postdoctoral years

 2010

“Cytotoxicity and Internalization of Polymer Hydrogel Capsules by Mammalian Cells”,
Zelikin, A.N.,* Kerry Breheney, Remy Robert, Elvira Tjipto, Kim Wark* Biomacromolecules 2010, 11, 2123-2129.

““Subcompartmentalized polymer hydrogel capsules with selectively degradable carriers and subunits”,
Kulygin, O.; Price, A.D.; Chong, S.-F.; Städler, B.; Zelikin, A.N.; Caruso, F.
Small 2010, 6, 1558-1564

“A Biomolecular “Ship-in-a-Bottle”: Continuous RNA Synthesis within Hollow Polymer Hydrogel Assemblies”,
Price, A.D.; Zelikin, A.N.; Wark, K.; Caruso, F.
Adv. Mater. 2010, 22, 720-723.

“Poly(L-lysine) nanostructured particles for gene delivery and hormone stimulation”,
Zhang, X.; Oulad-Abdelghani, M.; Zelikin, A.N.; Wang, Y.; Haîkel, Y.; Mainard, M.; Voegel, J.-C.; Caruso, F.; Benkirane-Jessel, N.
Biomaterials  2010, 31, 1699-1706

 2009

“Tuning the Formation and Degradation of Layer-by-Layer Assembled Polymer Hydrogel Microcapsules”,
Becker, A.L.; Zelikin, A.N.; Johnston, A.P.R.; Caruso, F.
Langmuir  2009, 25, 14079-14085.

“A Protective Vaccine Delivery System for in vivo T cell Stimulation using Nanoengineered Polymer Hydrogel Capsules”,
Sexton, A; Whitney, P.; Chong, S.-F.; Zelikin, A.N.; Johnston, A.P.R.; De Rose, R.; Brooks, A.; Caruso, F.; Kent, S.
ACS Nano 2009, 3, 3391-3400.

“Stabilization of Polymer Hydrogel Capsules via Thiol–Disulfide Exchange”,
Chong, S.-F.; Chandrawati, R.; Städler, B.; Park, J.; Cho, J.; Wang, Y.; Jia, Z.; Bulmus, V.; Davis, T.P.; Zelikin, A.N.; Caruso, F.
Small 2009, 5, 2601-2610.

“Polymer hydrogel capsules: en route towards synthetic cellular systems”,
Städler, B.; Price, A.D.; Chandrawati, R.; Hosta-Rigau, L.; Zelikin, A.N.; Caruso, F.
Nanoscale 2009, 1, 68-73
Featured on the inside cover of the inaugural volume of the journal
Highlighted in Highlights in Chemical Biology

“Cholesterol-mediated anchoring of enzyme-loaded liposomes within disulfide-stabilized polymer carrier capsules”,
Chandrawati, R.; Städler, B.; Postma, A.; Connal, L.A.; Chong, S.-F.; Zelikin, A.N.; Caruso, F.
Biomaterials 2009, 30, 5988-5998.

“A Paradigm for Peptide Vaccine Delivery Using Viral Epitopes Encapsulated in Degradable Polymer Hydrogel Capsules”,
Chong, S.-F.; Sexton, A.; De Rose, R.; Kent, S.J.; Zelikin, A.N.; Caruso, F.
Biomaterials 2009, 30, 5178-5186.

“Self-Polymerization of Dopamine as a Versatile and Robust Technique to Prepare Polymer Capsules”,
Postma, A.; Yan Yan, Wang, Y.; Zelikin, A.N.; Tjipto, E.; Caruso, F.
Chem. Mater. 2009, 21, 3042-3044.

“A Microreactor with Thousands of Subcompartments: Enzyme-Loaded Liposomes within Polymer Capsules”,
Städler, B.; Chandrawati, R.; Price, A.D.; Chong, S.-F.; Breheney, K.; Postma, A.; Connal, L.A.; Zelikin, A.N.; Caruso, F.
Angew. Chemie Int. Ed. 2009, 48, 4359-4362

Featured as a “Hot Paper” on the Publishers website
Highlighted in Chemistry in Australia
Highlighted online on the AAAS www.eurekalert.org website)

“Degradable, Surfactant-free, Monodisperse Polymer-Encapsulated Emulsions as Anti-Cancer Drug Carriers”,
Sivakumar, S.; Bansal, V.; Cortez, C.; Chong, S.-F.; Zelikin, A.N.; Caruso, F.
Adv. Mater. 2009, 21, 1820-1824.

“Triggered Enzymatic Degradation of DNA within Selectively Permeable Polymer Capsule Microreactors”,
Price, A.D.; Zelikin, A.N.; Wang, Y.; Caruso, F.
Angew. Chemie Int. Ed. 2009, 48, 329-332.

Highlighted in Chemistry in Australia

“Stabilization and Functionalization of Polymer Multilayers and Capsules via Thiol–ene Click Chemistry”,
Connal, L.; Kinnane, C.; Zelikin, A.N.; Caruso, F.
Chem. Mater. 2009, 21, 576-578.

2008

“Binding, Internalisation and Antigen Presentation of Vaccine-Loaded Nanoengineered Capsules in Blood”,
De Rose, R.; Zelikin, A.N.; Johnston, A.P.R.; Sexton, A.; Chong, S.-F.; Cortez, C.; Mulholland, W.; Caruso, F.; Kent, S.J.

Adv. Mater. 2008, 20, 4698-4703.

 

“Microfluidic Polymer Multilayer Adsorption on Liquid Crystal Droplets for Microcapsule Synthesis”,
Priest, C.; Quinn, A.; Postma, A.; Zelikin, A.N.; Ralston, J.; Caruso, F.
Lab Chip 2008, 8, 2182-2187.

“Disulfide-Stabilized Poly(methacrylic acid) Capsules: Formation, Cross-Linking, and Degradation Behaviour”,
Zelikin, A.N.; Li, Q.; Caruso, F.

Chem. Mater. 2008, 20, 2655-2661.

 

“Characterization of the Growth of Polyelectrolyte Multilayers Formed at Interfaces between Aqueous Phases and Thermotropic Liquid Crystals”,
Gupta, J.K.; Tjipto, E.; Zelikin, A.N.; Caruso, F.; Abbott, N.L.
Langmuir 2008, 24, 5534-5542.

“Templated Synthesis of Single-Component Polymer Capsules and Their Application in Drug Delivery”,
Wang, Y.; Bansal, V.; Zelikin, A.N.; Caruso, F.
Nano Lett. 2008, 8, 1741-1745.

 

2007

“A General Approach for DNA Encapsulation in Degradable Polymer Microcapsules”, Zelikin A.N.; Becker A.L.; Johnston A.P.R.; Wark K.L.; Turatti F.; Caruso F.
ACS Nano 2007, 1, 63-69.
Featured on the inaugural cover page of the journal;# 5 Most-cited publication in ACS Nano.

“Assembling DNA into Advanced Materials: From Nanostructured Films to Biosensing and Delivery Systems”,
Johnston, A.P.R.; Zelikin, A.N.; Caruso, F.
Adv. Mater. 2007, 19, 3727-3730.

“Poly(vinylpyrrolidone) for Bioconjugation and Surface Ligand Immobilization”,
Zelikin, A.N.*; Such, G.K.; Postma, A.; Caruso, F.
Biomacromolecules 2007, 8, 2950-2953.

“Next Generation, Sequentially Assembled Ultrathin Films: Beyond Electrostatics”,
Quinn, J.F.; Johnston, A.P.R.; Such, G.K.; Zelikin, A.N.; Caruso, F.
Chem. Soc. Rev. 2007, 36, 707-718.
Ranked in the top ten most accessed publications during May 2007 recognized within the Top 50 articles published in 2007.

 

2006

“Degradable Polyelectrolyte Capsules Filled with Oligonucleotide Sequences”,
Zelikin, A.N.; Qi Li; Caruso, F.
Angew. Chemie Int. Ed. 2006, 45, 7743-7745.
Featured as a “Hot Paper” on the Publishers’ website

“Approaches to Quantifying and Visualizing Polyelectrolyte Multilayer Film Formation on Particles”,
Johnston, A.P.R.; Zelikin, A.N.; Lee, L.; Caruso, F.
Anal. Chem. 2006, 78, 5913-5919.

“Disulfide Cross-Linked Polymer Capsules: En Route to Biodeconstructible Systems”,
Zelikin, A.N.; Quinn, J.F.; Caruso, F.
Biomacromolecules 2006, 7, 27-30.
# 1 most cited publication in Biomacromolecules in 2006 ; Featured in Top 20 most cited manuscripts in Biomacromolecules

Cornell University postdoctoral years

“Diblock Copolymers Based on Dihydroxyacetone and Ethylene Glycol: Synthesis, Characterization, and Nanoparticle Formulation”, Zawaneh, P.N.; Doody, A.M.; Zelikin, A.N.; Putnam, D.
Biomacromolecules 2006, 7, 3245-3251.

“A Functionalizable Biomaterial Based on Dihydroxyacetone, an Intermediate of Glucose Metabolism”,
Zelikin, A.N.; Zawaneh, P.N.; Putnam, D.
Biomacromolecules 2006, 7, 3239-3244.

2005

“Poly(carbonate-acetal)s from the Dimer Form of Dihydroxyacetone”,
Zelikin, A.N.; Putnam, D.
Macromolecules 2005, 38, 5532-5537.
“Structure–Function Relationships of Gene Delivery Vectors in a Limited Polycation Library”,
Chen, D.J.; Majors, B.S.; Zelikin, A.; Putnam, D.
J. Controlled Release 2005, 103, 273-283.

 

Ph.D. project and MIT projects

“Recognition and Selective Binding of DNA by Ionenes of Different Charge Density”,

Trukhanova, E.S., Izumrudov, V.A.; Litmanovich, A.A.; Zelikin, A.N.*
Biomacromolecules 2005, 6, 3198-3201.

 

2004

“Conformation of Polyelectrolyte Chains in Dilute Aqueous Solutions Investigated by Conductometry. 4. Influence of Molecular Mass and Charge Density of the Chains on Conformation of Symmetrical Aliphatic Ionene Bromides”, Zelikin, A.N.; Davydova, O.V.; Akritskaya, N.I.; Kargov, S.I.; Izumrudov, V.A.
J. Phys. Chem. B 2004, 108, 490-495.

2003

“Competitive Reactions in Solutions of Poly-L-histidine, Calf Thymus DNA and Synthetic Polyanions. Determining of the Binding Constants of Polyelectrolytes”,
Zelikin, A.N.; Trukhanova, E.S.; Putnam, D.; Izumrudov, V.A.; Litmanovich, A.A.
J. Am. Chem. Soc. 2003, 125, 13693-13699.

 

“Polyhistidine-PEG:DNA Nanocomposites for Gene Delivery”,
Putnam, D.; Zelikin, A.N.; Izumrudov, V.A.; Langer, R.
Biomaterials 2003, 24, 4425-4433

“Interpolyelectrolyte Reactions in Solutions of Polycarboxybetaines”,
Izumrudov, V.A.; Zelikin, A.N.; Zhiryakova, M.V.; Jaeger, W.; Bohrisch, J.
J. Phys. Chem. B 2003, 107, 7982-7986.

“Conformational Changes of Aliphatic Ionenes in Water-Salt Solutions as a Factor Controlling Stability of Their Complexes with Calf Thymus DNA”,
Zelikin, A.N.; Litmanovich, A.A.; Paraschuk, V.V.; Sybatchin, A.V.; Izumrudov, V.A.
Macromolecules 2003, 36, 2066-2071.

“Selectivity of Binding of Aliphatic Ionene with DNA and Sodium Polyacrylate”,
Zelikin, A.N.*, Trukhanova, E.S.; Izumrudov, V.A.; Litmanovich, A.A.
Polymer Science, Ser. B 2003, 45, 284-288.

2002

“Aliphatic Ionenes as Gene Delivery Agents: Elucidation of Structure-Function Relationship Through Modification of Charge Density and Polymer Length”,
Zelikin A.N.; Putnam, D.; Shastri, P.; Langer, R.; Izumrudov, V.A.

Bioconjugate Chem. 2002, 13, 548-553.

 

“Conformation of Polyelectrolyte Chains in Dilute Aqueous Solutions Investigated by Conductometry, 3. Influence of Charge Density on the Conformation of Partly Alkylated Poly(N-ethyl-4-vinylpyridinium) Cations and Ionenes”,
Davydova, O.V.; Zelikin, A.N.; Kargov, S.I.; Izumrudov, V.A.
Macromol. Chem. Phys. 2002, 203, 837-844.

“Polyelectrolyte Complexes Formed by Calf Thymus DNA and Aliphatic Ionenes: Unexpected Change in Stability upon Variation of Chain Length of the Ionenes of Different Charge Density”,
Zelikin, A.N.; Izumrudov, V.A.
Macromol. Biosci. 2002, 2, 78-81.

“Erodible Conducting Polymers for Potential Biomedical Applications”,
Zelikin, A.N.; Lynn, D.M.; Farhadi, J.; Martin, I.; Shastri, V.; Langer, R.
Angew. Chemie Int. Ed. 2002, 41, 141-144.

2001

“Synthesis of synthetic polymers: Polyanhydrides” in “Methods of Tissue Engineering”,
Anthony Atala and Robert P. Lanza, Eds., Academic Press 2001, Chapter 52, Pages 609-618.
Shastri, V.P.; Zelikin, A.; Hildgen, P.

“Modified Aliphatic Ionenes. Influence of Charge Density and Length of the Chains on Complex Formation with Poly(methacrylic acid)”,
Zelikin A.N.; Akritskaya, N.I.; Izumrudov, V.A.
Macromol. Chem. Phys. 2001, 202, 3018-3026.

“Conformation of Polyelectrolyte Chains in Dilute Aqueous Solutions Investigated by Conductometry. 2. Influence of Temperature, Chain Length and N-alkyl Substituent on Conformation of Exhaustively Alkylated Poly(N-alkyl-4-vinylpyridinium) Cations”,
Davydova, O.V.; Zelikin, A.N.; Kargov, S.I.; Izumrudov, V.A.
Macromol. Chem. Phys. 2001, 202, 1368-1373.

“Conformation of Polyelectrolyte Chains in Dilute Aqueous Solutions Investigated by Conductometry. 1. Influence of the Degree of Polymerization on the Conformation of Flexible Vinylic Polyanions and Rigid Native DNA”,
Davydova, O.V.; Zelikin, A.N.; Kargov, S.I.; Izumrudov, V.A.
Macromol. Chem .Phys. 2001, 202 (8), 1361-1367.
 

1999

“Facile Synthesis of 3-alkylpyrroles”,
Zelikin, A.N.; Shastri, P.; Langer, R.
J. Org. Chem. 1999, 64, 3379-3380.

CONFERENCE PAPERS

“Encapsulation of DNA within Degradable Polymeric Microcapsules”,
Caruso, F.; Zelikin, A.N.; Becker, A.L.; Johnston, A.P.R.; Turatti, F.; Wark, K.
PMSE Preprints 2008, 99, 723.
“Mesoporous Particle-Directed Synthesis of Advanced Polymer Capsules”,
Caruso, F.; Wang, Y.; Bansal, V.; Zelikin, A.N.
PMSE Preprints 2008, 99, 150.
“Reversible Encapsulation of DNA into Semipermeable Polymer Capsules”,
Zelikin, A.N.; Becker, A.L.; Qi Li; Wark, K.; Caruso, F.
PMSE Preprints 2007, 97, 34.
“Selectivity of Binding of Polycations to DNA and Synthetic Polyanions”,
Zelikin, A.N.; Trukhanova, E.S.; Putnam, D.A.; Izumrudov, V.A.; Litmanovich, A.A.
Polymer Preprint 2003, 44, 519-520.
“Bioerodible Polypyrrole”,
Zelikin, A.; Shastri, V.; Lynn, D.; Farhadi, J.; Martin, I.; Langer, R.
Mat. Res. Soc. Symp. Proc. 2002, 711, 193-197.

PATENTS

Shastri, V.P.; Zelikin, A.; Lynn, D. Bioerodible conducting materials and their preparation.
PCT Int. Appl. (2003), 29 pp. CODEN: PIXXD2 WO 2003000860 A2 20030103

Putnam, D.; Zelikin, A. Dihydroxyacetone-based polymers and preparation thereof.
PCT Int. Appl. (2005), 22 pp. CODEN: PIXXD2 WO 2005108457 A1 20051117