 | "Non-covalent hitchhiking on endogenous carriers as a protraction mechanism for antiviral macromolecular prodrugs" Frich, Camilla Kaas; Krüger, Franziska; Walther, Raoul; Domar, Cecilie; Andersen, Anna H. F.; Tvilum, Anne; Dagnæs-Hansen, Frederik; Denton, Paul W.; Tolstrup, Martin; Paludan, Søren R.; Münch, Jan; Zelikin, Alexander N. Journal of Controlled Release 2019, 294(), 298-310 |
 | "Innate glycosidic activity in metallic implants for localized synthesis of antibacterial drugs" ter Meer, Marja; Dillion, Ross; Nielsen, Signe Maria; Walther, Raoul; Meyer, Rikke L.; Daamen, Willeke F.; van den Heuvel, Lambertus P.; van der Vliet, J. Adam; Lomme, Roger M. L. M.; Hoogeveen, Yvonne L.; Schultze Kool, Leo J.; Schaffer, Jeremy E.; Zelikin, Alexander N. Chemical Communications 2019, 56(4), 443-446 |
 | "Identification and Directed Development of Non-Organic Catalysts with Apparent Pan-Enzymatic Mimicry into Nanozymes for Efficient Prodrug Conversion" Walther, Raoul; Winther, Anna K.; Fruergaard, Anne Sofie; van den Akker, Wouter; Sørensen, Lise; Nielsen, Signe Maria; Jarlstad Olesen, Morten T.; Dai, Yitao; Jeppesen, Henrik S.; Lamagni, Paolo; Savateev, Aleksandr; Pedersen, Søren Lykke; Frich, Camilla Kaas; Vigier-Carrière, Cécile; Lock, Nina; Singh, Mandeep; Bansal, Vipul; Meyer, Rikke L.; Zelikin, Alexander N. Angewandte Chemie International Edition 2019, 58(1), 278-282 |
 | "Bi-Enzymatic Embolization Beads for Two-Armed Enzyme-Prodrug Therapy" Olesen, Morten T. Jarlstad; Winther, Anna K.; Fejerskov, Betina; Dagnaes-Hansen, Frederik; Simonsen, Ulf; Zelikin, Alexander N. ADVANCED THERAPEUTICS 2018, 0(0), 1800023 |
 | "Long-Acting, Potent Delivery of Combination Antiretroviral Therapy" Andersen, Anna H. F.; Riber, Camilla F.; Zuwala, Kaja; Tolstrup, Martin; Dagnæs-Hansen, Frederik; Denton, Paul W.; Zelikin, Alexander N. ACS Macro Letters 2018, 7(5), 587-591 |
 | "Macromolecular prodrugs of ribavirin: Polymer backbone defines blood safety, drug release, and efficacy of anti-inflammatory effects" Zuwala, Kaja; Riber, Camilla F.; Løvschall, Kaja Borup; Andersen, Anna H. F.; Sørensen, Lise; Gajda, Paulina; Tolstrup, Martin; Zelikin, Alexander N. Journal of Controlled Release 2018, 275(), 53-66 |
 | "Enzyme Prodrug Therapy Achieves Site-Specific, Personalized Physiological Responses to the Locally Produced Nitric Oxide" Winther, Anna K.; Fejerskov, Betina; ter Meer, Marja; Jensen, Najah B. S.; Dillion, Ross; Schaffer, Jeremy E.; Chandrawati, Rona; Stevens, Molly M.; Schultze Kool, Leo J.; Simonsen, Ulf; Zelikin, Alexander N. ACS Applied Materials & Interfaces 2018, 10(13), 10741-10751 |
 | "The molecular tweezer CLR01 inhibits Ebola and Zika virus infection" Röcker, Annika E.; Müller, Janis A.; Dietzel, Erik; Harms, Mirja; Krüger, Franziska; Heid, Christian; Sowislok, Andrea; Riber, Camilla Frich; Kupke, Alexandra; Lippold, Sina; von Einem, Jens; Beer, Judith; Knöll, Bernd; Becker, Stephan; Schmidt-Chanasit, Jonas; Otto, Markus; Vapalahti, Olli; Zelikin, Alexander N.; Bitan, Gal; Schrader, Thomas; Münch, Jan Antiviral Research 2018, 152(), 26-35 |
 | "Macromolecular Antiviral Agents against Zika, Ebola, SARS, and Other Pathogenic Viruses" Schandock, Franziska; Riber, Camilla Frich; Röcker, Annika; Müller, Janis A.; Harms, Mirja; Gajda, Paulina; Zuwala, Kaja; Andersen, Anna H. F.; Løvschall, Kaja Borup; Tolstrup, Martin; Kreppel, Florian; Münch, Jan; Zelikin, Alexander N. Advanced Healthcare Materials 2017, 6(23), 1700748 |
 | "Synthetic Polymer with a Structure-Driven Hepatic Deposition and Curative Pharmacological Activity in Hepatic Cells" Riber, Camilla Frich; Andersen, Anna Halling Folkmar; Rolskov, Lærke Anegaard; Zuwala, Kaja; Gajda, Paulina; Løvschall, Kaja Borup; Dagnæs-Hansen, Frederik; Banda, Dominic H.; Pietschmann, Thomas; Tolstrup, Martin; Zelikin, Alexander N. ACS Macro Letters 2017, (), 935-940 |
 | "Enzyme Prodrug Therapy Engineered into Electrospun Fibers with Embedded Liposomes for Controlled, Localized Synthesis of Therapeutics" Chandrawati, Rona; Olesen, Morten T. J.; Marini, Thatiane C. C.; Bisra, Gurpal; Guex, Anne Géraldine; de Oliveira, Marcelo G.; Zelikin, Alexander N.; Stevens, Molly M. Advanced Healthcare Materials , (), 1700385-n/a |
 | "Prodrugs in medicinal chemistry and enzyme prodrug therapies" Walther, Raoul; Rautio, Jarkko; Zelikin, Alexander N. Advanced Drug Delivery Reviews , 118(), 65-77 |
 | "Recent advances in macromolecular prodrugs" Riber, Camilla Frich; Zelikin, Alexander N. Current Opinion in Colloid & Interface Science 2017, 31(), 1-9 |
 | "Preparation, single-molecule manipulation and energy transfer investigation of a polyfluorene-graft-DNA polymer" Madsen, Mikael; Christensen, Rasmus S.; Krissanaprasit, Abhichart; Bakke, Mette R.; Riber, Camilla F.; Nielsen, Karina S.; Zelikin, Alexander; Gothelf, Kurt Vesterager Chemistry – A European Journal , (), n/a-n/a |
 | "Substrate Mediated Enzyme Prodrug Therapy" Fejerskov, Betina; Jarlstad Olesen, Morten T.; Zelikin, Alexander N. Advanced Drug Delivery Reviews 2017, (), |
 | "Localized and Controlled Delivery of Nitric Oxide to the Conventional Outflow Pathway via Enzyme Biocatalysis: Toward Therapy for Glaucoma" Chandrawati, Rona; Chang, Jason Y. H.; Reina-Torres, Ester; Jumeaux, Coline; Sherwood, Joseph M.; Stamer, W. Daniel; Zelikin, Alexander N.; Overby, Darryl R.; Stevens, Molly M. Advanced Materials 2017, 29(16), 1604932 |
 | "Macromolecular Prodrugs of Ribavirin: Structure–Function Correlation as Inhibitors of Influenza Infectivity" Riber, Camilla Frich; Hinton, Tracey M.; Gajda, Paulina; Zuwala, Kaja; Tolstrup, Martin; Stewart, Cameron; Zelikin, Alexander N. Molecular Pharmaceutics 2016, 14(1), 234–241 |
 | "Materials and methods for delivery of biological drugs" Zelikin, Alexander N.; Ehrhardt, Carsten; Healy, Anne Marie Nat Chem 2016, 8(11), 997-1007 |
 | "Albumin–Polymer–Drug Conjugates: Long Circulating, High Payload Drug Delivery Vehicles" Smith, Anton A. A.; Zuwala, Kaja; Pilgram, Oliver; Johansen, Karen Singers; Tolstrup, Martin; Dagnæs-Hansen, Frederik; Zelikin, Alexander N. ACS Macro Letters 2016, 5(10), 1089-1094 |
 | "Triple Activity of Lamivudine Releasing Sulfonated Polymers against HIV-1" Danial, Maarten; Andersen, Anna Halling Folkmar; Żuwała, Kaja; Cosson, Steffen; Riber, Camilla Frich; Smith, Anton A. A.; Tolstrup, Martin; Moad, Graeme; Zelikin, Alexander N.; Postma, Almar Molecular Pharmaceutics 2016, 13(7), 2397-2410 |
 | "Polyanionic Macromolecular Prodrugs of Ribavirin: Antiviral Agents with a Broad Spectrum of Activity" Hinton, Tracey M.; Zuwala, Kaja; Deffrasnes, Celine; Todd, Shawn; Shi, Shuning; Marsh, Glenn A.; Dearnley, Megan; Wohl, Benjamin M.; Tolstrup, Martin; Zelikin, Alexander N. Advanced Healthcare Materials 2016, 5(5), 534-540 |
 | "HIV anti-latency treatment mediated by macromolecular prodrugs of histone deacetylase inhibitor, panobinostat" Zuwala, Kaja; Smith, Anton; Tolstrup, Martin; Zelikin, Alexander Chemical Science 2016, 7(3), 2353-2358 |
 | "Tools of gene transfer applied to the intracellular delivery of non-nucleic acid polyanionic drugs" Kryger, Mille B. L.; Pedersen, Søren L.; Wohl, Benjamin M.; Zelikin, Alexander N. Chemical Communications 2016, 52(5), 889-891 |
 | "Phospholipid—polymer amphiphile hybrid assemblies and their interaction with macrophages" Panneerselvam, Karthiga; Lynge, Martin E.; Riber, Camilla Frich; Mena-Hernando, Sofia; Smith, Anton A. A.; Goldie, Kenneth N.; Zelikin, Alexander N.; Städler, Brigitte Biomicrofluidics 2015, 9(5), 052610 |
 | "Routing of individual polymers in designed patterns" Knudsen, Jakob Bach; Liu, Lei; Bank Kodal, Anne Louise; Madsen, Mikael; Li, Qiang; Song, Jie; Woehrstein, Johannes B.; Wickham, Shelley F. J.; Strauss, Maximilian T.; Schueder, Florian; Vinther, Jesper; Krissanaprasit, Abhichart; Gudnason, Daniel; Smith, Anton Allen Abbotsford; Ogaki, Ryosuke; Zelikin, Alexander N.; Besenbacher, Flemming; Birkedal, Victoria; Yin, Peng; Shih, William M.; Jungmann, Ralf; Dong, Mingdong; Gothelf, Kurt V. Nat Nano 2015, 10(10), 892-898 |
 | "Self-Immolative Linkers Literally Bridge Disulfide Chemistry and the Realm of Thiol-Free Drugs" Riber, Camilla Frich; Smith, Anton A. A.; Zelikin, Alexander N. Advanced Healthcare Materials 2015, 4(12), 1887-1890 |
 | "Micro-structured, spontaneously eroding hydrogels accelerate endothelialization through presentation of conjugated growth factors" Jensen, Bettina E. B.; Edlund, Katrine; Zelikin, Alexander N. Biomaterials 2015, 49(0), 113-124 |
drugs-with-concurrent-direct-activity-against-the-hepatitis-C-virus-and-inflammation_small.png) | "Macromolecular (pro)drugs with concurrent direct activity against the hepatitis C virus and inflammation" Wohl, Benjamin M.; Smith, Anton A. A.; Jensen, Bettina E. B.; Zelikin, Alexander N. Journal of Controlled Release 2014, 196(0), 197-207 |
 | "Disulfide reshuffling triggers the release of a thiol-free anti-HIV agent to make up fast-acting, potent macromolecular prodrugs" Kock, Anders; Zuwala, Kaja; Smith, Anton A. A.; Ruiz-Sanchis, Pau; Wohl, Benjamin M.; Tolstrup, Martin; Zelikin, Alexander N. Chemical Communications 2014, 50(93), 14498-14500 |
 | "Macromolecular prodrugs of ribavirin: towards a treatment for co-infection with HIV and HCV" Smith, Anton A. A.; Zuwala, Kaja; Kryger, Mille B. L.; Wohl, Benjamin M.; Guerrero-Sanchez, Carlos; Tolstrup, Martin; Postma, Almar; Zelikin, Alexander N. Chemical Science 2015, 6(1), 264-269 |
 | "Highly Active Macromolecular Prodrugs Inhibit Expression of the Hepatitis C Virus Genome in the Host Cells" Ruiz-Sanchis, Pau; Wohl, Benjamin M.; Smith, Anton A. A.; Zuwala, Kaja; Melchjorsen, Jesper; Tolstrup, Martin; Zelikin, Alexander N. Advanced Healthcare Materials 2015, 4(1), 65-68 |
 | "Macromolecular (pro)drugs in antiviral research" Smith, Anton A. A.; Kryger, Mille B. L.; Wohl, Benjamin M.; Ruiz-Sanchis, Pau; Zuwala, Kaja; Tolstrup, Martin; Zelikin, Alexander N. Polymer Chemistry 2014, 5(22), 6407-6425 |
 | "Enzyme Prodrug Therapy Engineered into Biomaterials" Mendes, Ana C.; Zelikin, Alexander N. Advanced Functional Materials 2014, 24(33), 5202-5210 |
 | "Polymers Fight HIV: Potent (Pro)Drugs Identified Through Parallel Automated Synthesis" Zuwala, Kaja; Smith, Anton A. A.; Postma, Almar; Guerrero-Sanchez, Carlos; Ruiz-Sanchis, Pau; Melchjorsen, Jesper; Tolstrup, Martin; Zelikin, Alexander N. Advanced Healthcare Materials 2015, 4(1), 46-50 |
 | "Cholesterol Modification of (Bio)Polymers Using UV-Vis Traceable Chemistry in Aqueous Solutions" Rasmussen, Kasper F.; Smith, Anton A. A.; Ruiz-Sanchis, Pau; Edlund, Katrine; Zelikin, Alexander N. Macromolecular Bioscience 2014, 14(1), 33-44 |
 | "Biocatalytic polymer thin films: optimization of the multilayered architecture towards in situ synthesis of anti-proliferative drugs" Andreasen, Sidsel O.; Fejerskov, Betina; Zelikin, Alexander N. Nanoscale 2014, 6(8), 4131-4140 |
 | "Macromolecular Prodrugs of Ribavirin: Concerted Efforts of the Carrier and the Drug" Smith, Anton A. A.; Wohl, Benjamin M.; Kryger, Mille B. L.; Hedemann, Natasha; Guerrero-Sanchez, Carlos; Postma, Almar; Zelikin, Alexander N. Advanced Healthcare Materials 2014, 3(9), 1404-1407 |
 | "Biocatalytic Polymer Coatings: On-Demand Drug Synthesis and Localized Therapeutic Effect under Dynamic Cell Culture Conditions" Fejerskov, Betina; Jensen, Najah B. S.; Teo, Boon M.; Städler, Brigitte; Zelikin, Alexander N. Small 2014, 10(7), 1314-1324 |
 | "The narrow therapeutic window of ribavirin as an inhibitor of nitric oxide synthesis is broadened by macromolecular prodrugs" Wohl, Benjamin M.; Smith, Anton A. A.; Kryger, Mille B. L.; Zelikin, Alexander N. Biomacromolecules 2013, 14(11), 3916–3926 |
 | "Macromolecular Prodrugs for Controlled Delivery of Ribavirin" Kryger, Mille B. L.; Smith, Anton A. A.; Wohl, Benjamin M.; Zelikin, Alexander N. Macromolecular Bioscience 2014, 14(2), 173-185 |
 | "Lipogels: Surface-Adherent Composite Hydrogels Assembled from Poly(Vinyl Alcohol) and Liposomes" Jensen, Bettina; Hosta-Rigau, Leticia; Spycher, Philipp; Reimhult, Erik; Stadler, Brigitte; Zelikin, Alexander Nanoscale 2013, 5(), 6758-6766 |
 | "Poly(vinyl alcohol) physical hydrogel nanoparticles, not polymer solutions, exert inhibition of nitric oxide synthesis in cultured macrophages" Andreasen, Sidsel; Chong, Siow-Feng; Wohl, Benjamin M.; Goldie, Kenneth N.; Zelikin, Alexander N. Biomacromolecules 2013, 14(5), 1687–1695 |
 | "Liposomal Templating, Association with Mammalian Cells, and Cytotoxicity of Poly(vinyl alcohol) Physical Hydrogel Nanoparticles" Andreasen, Sidsel Ø; Chong, Siow-Feng; Kryger, Mille B. L.; Jensen, Bettina E. B.; Postma, Almar; Alves, Marie-Helene; Städler, Brigitte; Goldie, Kenneth N.; Zelikin, Alexander N. Particle & Particle Systems Characterization 2013, 5(8), 2967–2975 |
 | "Macromolecular Prodrugs of Ribavirin Combat Side Effects and Toxicity with No Loss of Activity of the Drug" Kryger, Mille; Wohl, Benjamin; Smith, Anton; Zelikin, Alexander Chemical Communications 2013, 49(), 2643-2645 |
 | "Bioresorbable Surface Adhered Enzymatic Microreactors Based on Physical Hydrogels of Poly(vinyl alcohol)" Fejerskov, Betina; Smith, Anton A. A.; Jensen, Bettina E. B.; Hussmann, Thomas; Zelikin, Alexander N. Langmuir 2013, 29(1), 344–354 |
 | "Microstructured, Functional PVA Hydrogels through Bioconjugation with Oligopeptides under Physiological Conditions" Chong, Siow-Feng; Smith, Anton A. A.; Zelikin, Alexander N. Small 2013, 9(6), 942–950 |
 | "Substrate Mediated Enzyme Prodrug Therapy" Fejerskov, Betina; Zelikin, Alexander N. PLoS ONE 2012, 7(11), e49619 |
 | "Engineering Surface Adhered Poly(vinyl alcohol) Physical Hydrogels as Enzymatic Microreactors" Fejerskov, Betina; Jensen, Bettina E. B.; Jensen, Najah B. S.; Chong, Siow-Feng; Zelikin, Alexander N. ACS Applied Materials & Interfaces 2012, 4(9), 4981–4990 |
 | "Surface adhered poly(vinyl alcohol) physical hydrogels as tools for rational design of intelligent biointerfaces" Jensen, B. E. B.; Alves, M. H.; Fejerskov, B.; Städler, B.; Zelikin, A. N. Soft Matter 2012, 8(17), 4625-4634 |
 | "Intelligent Polymer Thin Films and Coatings for Drug Delivery" Zelikin, Alexander N.; Städler, Brigitte Book chapter in “Intelligent Surfaces in Biotechnology: Scientific and Engineering Concepts, Enabling Technologies, and Translation to Bio-Oriented Applications” 2012, (), 243-290 |
 | "Macromolecular design of poly(vinyl alcohol) by RAFT polymerization" Smith, A. A. A.; Hussmann, T.; Elich, J.; Postma, A.; Alves, M. H.; Zelikin, A. N. Polymer Chemistry 2012, 3(1), 85-88 |
 | "Poly(vinyl alcohol) physical hydrogels: New vista on a long serving biomaterial" Alves, M. H.; Jensen, B. E. B.; Smith, A. A. A.; Zelikin, A. N. Macromolecular Bioscience 2011, 11(10), 1293-1313 |
 | "Poly(vinyl alcohol) physical hydrogels: Noncryogenic stabilization allows nano- and microscale materials design" Jensen, B. E. B.; Smith, A. A. A.; Fejerskov, B.; Postma, A.; Senn, P.; Reimhult, E.; Pla-Roca, M.; Isa, L.; Sutherland, D. S.; Städler, B.; Zelikin, A. N. Langmuir 2011, 27(16), 10216-10223 |
 | "Exploiting fluorescent polymers to probe the self-assembly of virus-like particles" Cadena-Nava, R. D.; Hu, Y.; Garmann, R. F.; Ng, B.; Zelikin, A. N.; Knobler, C. M.; Gelbart, W. M. Journal of Physical Chemistry B 2011, 115(10), 2386-2391 |
 | "A critical look at multilayered polymer capsules in biomedicine: Drug carriers, artificial organelles, and cell mimics" Städler, B.; Price, A. D.; Zelikin, A. N. Advanced Functional Materials 2011, 21(1), 14-28 |
 | "Poly(methacrylic acid) polymer hydrogel capsules: Drug carriers, sub-compartmentalized microreactors, artificial organelles" Zelikin, A. N.; Städler, B.; Price, A. D. Small 2010, 6(20), 2201-2207 |
 | "Drug releasing polymer thin films: New era of surface-mediated drug delivery" Zelikin, A. N. ACS Nano 2010, 4(5), 2494-2509 |
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