Macromolecular Prodrugs of Ribavirin: Concerted Efforts of the Carrier and the Drug

Our next publication on antiviral polymer therapeutics entitled “Macromolecular Prodrugs of Ribavirin: Concerted Efforts of the Carrier and the Drug” has been published in Advanced Healthcare Materials.

abstract

Polymers in tune. Automated parallel polymer synthesis is developed to obtain libraries of macromolecular prodrugs of ribavirin, a broad-spectrum antiviral agent. As many as 10 identified lead polymer conjugates exhibit therapeutic efficacy matching that of the pristine drug and at the same time suppressed the origin of the main side effect of ribavirin.